There are likely many more ways that caffeine works to reduce headache pain that aren’t fully understood. Since caffeine prevents the dilation of blood vessels, it tends to prevent headaches. Caffeine has vasoconstrictive properties, meaning it narrows blood vessels, restricting blood flow. How exactly does caffeine improve headache treatments?īlood vessels tend to dilate before a headache. But there’s no scientific evidence that caffeine doesn’t reduce other kinds of headaches.Įither way, it seems that caffeine can reduce pain from headaches, or at least increase the strength of your pain medication. Most of the studies on caffeine and headaches look at tension headaches and migraine specifically. This review found that caffeine “significantly” boosted the efficacy of OTC headache treatments. It included more studies than the previous review. This review looked at the use of caffeine for many different pain conditions, not just headache.Ī more recent review also looked at whether caffeine improves the efficacy of analgesics when it comes to treating headaches. However, the improvement was small and was called “statistically insignificant” by the study’s authors. In some cases, caffeine may ease headaches and enhance over-the-counter (OTC) headache treatments.Ī 2014 review, which looked at the results of 20 different studies with a total of 4262 participants, found that caffeine slightly enhances the efficacy of analgesics like ibuprofen (Advil) or acetaminophen (Tylenol).
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